Study finds antibiotic-resistant infections in children in Bangladesh

Study finds antibiotic-resistant infections in children in Bangladesh
A study conducted at a hospital in Dhaka, Bangladesh, has found high levels of antibiotic-resistant bacterial infections in children under 5 years with pneumonia in Bangladesh. Around 18% of bacteria isolated from children with pneumonia were resistant to all routinely used antibiotics.
For the new study, the researchers said that they analyzed the records of 4,007 children under 5 years admitted to the Dhaka Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh between 2014 and 2017 with pneumonia.
The researchers found that in cases where bacteria were resistant to all routinely used antibiotics, 17 times as many children died as those without a blood infection. They also found that 18% of the positive cultures were resistant to all routinely used antibiotics including ampicillin, gentamicin, ciprofloxacin, and ceftriaxone. The authors of the study pointed out how these findings suggest that the emerging pandemic of antibiotic-resistant bacterial infection is already taking a toll on young children in Dhaka, Bangladesh.
Co-author Jason Harris, chief of the division of Pediatric Global Health at Massachusetts General Hospital for Children in Boston, highlighted the urgent need for better diagnostic tests and better availability of appropriate medicines for kids who might otherwise die from their infections.
“We’ve seen from COVID-19 and [COVID-19] variants how we live in a global community. Like COVID, superbugs already have and continue to spread around the world because antibiotic resistance gives these bacteria a competitive advantage.”
The authors also shared the limitations of the study, that the cause of infection in the 6% of children with positive blood cultures is unlikely to reflect the causes in the wider group and that they were unable to account for previous antibiotic use among the children.The research was a collaboration between scientists in Bangladesh and the United States and appeared in the medical journal Open Forum Infectious Diseases.