Senmao Zhang et al demonstrated a significant association between parental alcohol consumption and the risk of congenital heart diseases (CHDs) in offspring. The team found that consumption of alcohol three months before pregnancy or during the first trimester was associated with a 44% increased risk of CHD for fathers and 16% for mothers, compared to not drinking. Binge drinking was related to a 52% higher likelihood of these birth defects for men and 16% for women. The researchers compiled data published between 1991 and 2019, which amounted to 55 studies including 41,747 babies with congenital heart disease and 297,587 without. A nonlinear dose-response relationship between parental alcohol exposure and risk of total CHDs was observed. With an increase in parental alcohol consumption, the risk of total CHDs in offspring also gradually increases. The research highlights the necessity of improving awareness to prevent alcohol exposure during preconception and conception periods.
Source: European Journal of Preventive Cardiology October 2, 2019 https://doi.org/10.1177/2047487319874530