Researchers at Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Banglore has developed a potential anti-microbial coating for medical devices and other personal protective supplies which could effectively kill influenza virus and many resistant pathogenic strains of bacteria and fungi. The scientists revealed that the covalent compound when coated on different surfaces such as textiles and plastic could kill a range of virus types including that of the novel coronavirus (nCoV).
The coated molecules chemically cross-linked with different surfaces upon UV irradiation. The coating induced formation of pores on the membranes of pathogens like bacteria leading to their inactivation. The JNCASR team said that the coating could completely kill resistant pathogenic strains of bacteria and fungi, including methicillin-resistant Staphylococcus aureus and fluconazole-resistant Candida albicans spp.
Molecules of the compound were designed based on their optimum solubility in a wide range of solvents involving water, ethanol, chloroform and a cost-effective three-to-four-step synthetic strategy with easy purification and high yield. The developed antimicrobial molecules were then immobilized on different substrates such as cotton, polyurethane, polypropylene and polystyrene, and evaluated for their effectiveness against different pathogenic organisms.
The study has been currently accepted in the journal–Applied Material and Interfaces. The researchers suggest that coating personal protective supplies such as masks, gloves, gowns, and other medical devices using the antimicrobial coating helps prevent and control the transmission of infections.