Heart failure mortality risk is higher than that of cancer in India; NHFR Study

Heart failure mortality risk is higher than that of cancer in India; NHFR Study

In India, the mortality risk of heart failure (HF) patients is about 17% for a 90-day duration which is higher than the fatality risk associated with cancer, revealed the first National Heart Failure Registry (NHFR) which was released on Monday.

The study stressed ischemic heart disease as the leading cause of heart failure observed in India. The 30-day mortality risk of heart failure patients was 12.2% while the risk was 6.4% for a 7-day duration. The disease burden is more on the younger generation (less than 65 years) when compared to that of other countries, emphasized the analysis.

The study conducted as part of the registry found that only less than half of the eligible patients received a guideline-based therapy which has showed to reduce the mortality risk in the patients.

“The higher 90-day mortality in heart failure (HF) patients calls for a nationwide audit and quality improvement initiatives,” says the NHFR.

The Indian Council of Medical Research (ICMR) funded NHFR is a multicentric, hospital-based registry of HF patients. The study recruited 200 HF patients from each of the 50 centres located across 24 states in India from January 2019.

Heart failure with reduced ejection fraction (HFrEF) was the most common form of presentation (65.6%), followed by HF with mid-range ejection fraction and HF with preserved ejection fraction. Ejection fraction is used to assess the pumping function of the heart as it represents the percentage of blood pumped from the left ventricle per beat.

“Ischemic heart disease was the predominant aetiology for HF (73%), followed by dilated cardiomyopathy in 17.2% of the population. Rheumatic valvular heart disease was prevalent in 5.9% of the study population,” said coordinator of NHFR Dr S Harikrishnan, who is also the national principal investigator.

Hypertension (48.5%) and diabetes (44.4%) were the most frequent co-morbid conditions for heart failure.