New radiomics method may reduce need for breast biopsies

February 5, 2019 0 By FM

Karen Drukker et al developed a novel technology that uses mammography to determine the biological tissue composition of a tumour that could help reduce unnecessary breast biopsies. The new technique, called three-compartment breast (3CB) imaging, measures the water, lipid and protein tissue composition characterising the tumour. The researchers acquired dual-energy mammograms from 109 women with Breast Imaging Reporting and Data System category 4 or 5 breast masses. The 3CB images were combined with mammography radiomics which showed positive predictive value in large breast masses. The combined method improved positive predictive value from 32% for visual interpretation to almost 50% with a reduction in biopsies to 36%. The 3CB-radiomics method missed one of the 35 cancers for a 97% sensitivity rate. The research suggests the need for further progress in studying how the combined approach would help radiologists in making their final determinations.

Source: n Radiology: Volume 00: Number 0—2019 Dec 11 2018