Hydrogel capsule for weight lossJune 11, 2019
Plenity manufactured by the Gelesis has been granted approval by USFDA as an aid in weight management in adults with a body mass index (BMI) of 25–40 kg/m2, when used in conjunction with diet and exercise.
It is an oral, non-systemic, superabsorbent hydrogel capsule which when taken together with diet and exercises aids in weight loss by inducing satiety and reducing hunger.
The drug can be administered in the form of capsules that could be taken with water before dinner and lunch. It is made of two naturally derived compounds called cellulose and citric acid which are cross linked together in a manner that they create a three-dimensional matrix.
The hydrogel-based capsule release thousands of non-aggregating gel-like particles that rapidly absorbs water in the stomach. These small gellike particles have an elasticity of plant-based foods but they do not have any caloric value. These gel particles increase the elasticity of the contents stored in the stomach and intestine giving out a feeling of fullness that aids in weight loss.
The clinical studies of Plenity have shown positive effects on weight management.