Robert M. G. Reinhart et al demonstrated that electrostimulation can improve the working memory of older adults by temporarily reversing the age-related cognitive decline. The study involved 42 people aged 20–29 years and 42 people aged 60–76 years and was assessed in a working memory task. The study showed that the core feature of cognitive decline was caused due to a disconnection between the two brain networks of the frontotemporal cortex. The researchers subjected the older participants to 25 minutes of non-invasive electrical stimulation across the brain using electrodes with frequency personalized to their individual brain circuits. After the stimulation the cohort showed a preferential increase in neural synchronization patterns between the frontotemporal regions of the brain. All participants were subjected to test their working memory. The results before and after stimulation were compared between the two cohorts. The findings revealed that the older participants showed a rapid improvement in working memory that lasted for 50 minutes post stimulation. The findings unveil a new approach towards non-pharmacological intervention in improving cognitive decline by targeting aspects of age-related cognitive impairment.
Source: Nature Neuroscience April 8,2019 https://www.nature.com/articles/s41593-019-0371-x