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Breakthrough study captures polygenic risk scores for CAD in South Asia

MedGenome Labs, leading genomics research and clinical data-driven diagnostics company, in collaboration with experts from Broad Institute of MIT and Harvard and others, conducted a first-ever study on Indian population that validates a novel ‘CAD-PRS’ (coronary artery disease-genome-wide polygenic risk score) to precisely predict the risk of developing a coronary artery disease/myocardial infarction (MI) using a person’s genetic makeup.

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Verve presents data on one-time gene editing to prevent heart diseases

The US biotechnology company Verve Therapeutics presented a new preclinical proof-of-concept data on successful use of base editing to turn off a gene in the liver and thereby lower blood levels of either LDL cholesterol or triglyceride-rich lipoproteins, two factors leading to coronary atherosclerosis.

C H Unnikrishnan

Intravenous analgesic oliceridine receives FDA approval for acute pain management

Oliceridine (Olinvyk), a first-in-class intravenous (IV) analgesic has recently received the US FDA approval for management of moderate to severe acute pain in adults.

FM

Russia to register world’s first COVID-19 vaccine tomorrow

Russia plans to register the world’s first vaccine against SARS CoV-2 infection on August 12, according to agency reports quoting Deputy Health Minister Oleg Gridnev.

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COVID-19: India reports more new cases than US and Brazil;Total tally crosses 2.26 million

India registered 53,601 new COVID positive cases on Monday. The country, which has been registering more number of new cases than the two most affected countries such as the US and Brazil in the last one week, has so far reported 2,268,675 positive cases in all.

FM

CanSino to begin phase 3 human trials for COVID-19 vaccine in Saudi Arabia

An adenoviral serotype 5 (Ad5) vectored COVID-19 vaccine candidate developed by the Chinese researchers is set to enter phase 3 clinical trial in Saudi Aradia, announced CanSino Biologics.

FM

Researchers develop device to help detect microtentacles on breast cancer cells

Researchers at the University of Maryland School of Medicine have developed a microfluidic device that could help preserve and detect the presence of thin membrane protrusions called “microtentacles” on breast cancer cells which can help image non-adherent cells to detect whether a tumour is likely to spread.

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