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Drug Resistance

Fewer drugs targeting resistant ‘superbugs’ in pipeline: WHO

Two new reports reveal a weak pipeline for antibiotic agents. The 60 products in development (50 antibiotics and 10 biologics) bring little benefit over existing treatments and very few targets gram-negative, the most critical resistant bacteria.

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Threat of resistant HIV

Global and large-scale use of anti-retroviral therapy (ART) is helping reduce relative rates of morbidity and mortality from acquired immunodeficiency syndrome.

Dr Rajani Kanth Vangala

Three million surgeries and cancer treatments may turn life-threatening

Public Health England’s (PHE’s) English Surveillance Programme for Antimicrobial Utilisation and Resistance (ESPAUR) report published in October highlights how more than 3 million common procedures such as cesarean sections and hip replacements could become life-threatening without antibiotics.

PIL questions unchecked antibiotics sale

A public interest litigation (PIL) has been registered in Bombay High Court demanding action to address unchecked sales of high potency antibiotics without prescriptions.

Tackling emerging pathogens

In India, the largest therapeutic group — which accounts for 15.7% of the drugs market — are antibiotics. This suggests not only that antibiotics are now available to a larger segment of needed people, but also irrational use, leading to antibiotic resistance in bugs.

Dr Rajani Kanth Vangala

Antibiotics from nematodes

Scientists have created a new class of antibiotics based on a mechanism employed by nematode worms to survive the onslaught of invading microbes.
Besides the unconventional origin, what makes this new antibiotic truly unique is its distinct modality of action, according to the joint team of researchers that discovered and developed the drugs.