Author: Krishna Unni

April 11, 2022 0

Omicron-L452R could be the most risky SARS CoV-2 variant

By Krishna Unni

While the Omicron variant is typically characterised as less pathogenic and more transmissible than the parental and previous variants, which may be due to crystal structure changes caused by over 30 mutations in the Spike protein, the researchers found in this investigation that the further mutation of L452R in the Omicron variant not only rescued fusogenicity but also strengthened the high infectivity.